CHMP2B Antikörper (N-Term)
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- Target Alle CHMP2B Antikörper anzeigen
- CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte, Schwein, Kaninchen, Rind (Kuh), Hund, Pferd, Meerschweinchen, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CHMP2B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- ASLFKKKTVD DVIKEQNREL RGTQRAIIRD RAALEKQEKQ LELEIKKMAK
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against Chmp2b. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Chmp2b
- Top Product
- Discover our top product CHMP2B Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 213 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))
- Andere Bezeichnung
- Chmp2b (CHMP2B Produkte)
- Synonyme
- ALS17 antikoerper, CHMP2.5 antikoerper, DMT1 antikoerper, VPS2-2 antikoerper, VPS2B antikoerper, 1190006E07Rik antikoerper, RGD1306781 antikoerper, chmp2b antikoerper, chmp2bl antikoerper, zgc:77025 antikoerper, si:ch211-224m9.5 antikoerper, CHMP2B antikoerper, cg4618 antikoerper, chmp2.5 antikoerper, dmt1 antikoerper, vps2-2 antikoerper, vps2b antikoerper, CHMP2b-B antikoerper, chmp2b-a antikoerper, chmp2b-b antikoerper, charged multivesicular body protein 2B antikoerper, charged multivesicular body protein 2Bb antikoerper, charged multivesicular body protein 2Ba antikoerper, charged multivesicular body protein 2B pseudogene antikoerper, charged multivesicular body protein 2B S homeolog antikoerper, charged multivesicular body protein 2B L homeolog antikoerper, CHMP2B antikoerper, Chmp2b antikoerper, chmp2bb antikoerper, chmp2ba antikoerper, LOC747711 antikoerper, chmp2b.S antikoerper, chmp2b.L antikoerper
- Hintergrund
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Chmp2b is involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Chmp2b recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Chmp2b redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery Chmp2b also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis. Involved in cytokinesis .
Alias Symbols: RGD1306781
Protein Size: 213 - Molekulargewicht
- 23 kDa
- Gen-ID
- 363720
- NCBI Accession
- XM_001063932, XP_001063932
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