ATG12 Antikörper (Middle Region)

Produktnummer ABIN2774065

Der Kaninchen Polyklonal Anti-ATG12-Antikörper wurde für WB und IHC validiert. Er ist geeignet, ATG12 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für ATG12 Antikörper (Middle Region) (ABIN2774065)

Target: ATG12 (Autophagy Related 12 (ATG12))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ATG12 Antikörper

Bindungsspezifität: Middle Region

Sequenz: KFLKLVASEQ LFIYVNQSFA PSPDQEVGTL YECFGSDGKL VLHYCKSQAW

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ATG12. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATG12

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 187 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ATG12

Target: ATG12 (Autophagy Related 12 (ATG12))

Andere Bezeichnung: ATG12

Hintergrund: Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).
Alias Symbols: APG12, APG12L, FBR93, HAPG12
Protein Interaction Partner: CRX, WIPI2, FADD, EXOC4, Atg10, ATG3, ATG5, CAV1, ATG16L1, WDFY3, APP, BCL2, MCL1, TECPR1, UBC, ATG7, ATG4B, GABARAP, MAP1B, KRTAP4-12, PLSCR1, MDFI, PTK2, DHX36, OTUD4, SF3B1, SF3A1, AUP1,
Protein Size: 187

Molekulargewicht: 21 kDa

Gen-ID: 9140

NCBI Accession: NM_004707, NP_004698

UniProt: O94817

Pathways: Autophagie