ATG12 Antikörper (Middle Region)

Produktnummer ABIN2774065

Der Kaninchen-Polyklonal Anti-ATG12-Antikörper wurde für WB und IHC validiert. Er ist geeignet zum Nachweis von ATG12 in Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Zebrafisch (Danio rerio). }

Kurzübersicht für ATG12 Antikörper (Middle Region) (ABIN2774065)

Target: ATG12 (Autophagy Related 12 (ATG12))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ATG12 Antikörper

Bindungsspezifität: Middle Region

Sequenz: KFLKLVASEQ LFIYVNQSFA PSPDQEVGTL YECFGSDGKL VLHYCKSQAW

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ATG12. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATG12

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 187 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ATG12

Target: ATG12 (Autophagy Related 12 (ATG12))

Andere Bezeichnung: ATG12

Hintergrund: Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).
Alias Symbols: APG12, APG12L, FBR93, HAPG12
Protein Interaction Partner: CRX, WIPI2, FADD, EXOC4, Atg10, ATG3, ATG5, CAV1, ATG16L1, WDFY3, APP, BCL2, MCL1, TECPR1, UBC, ATG7, ATG4B, GABARAP, MAP1B, KRTAP4-12, PLSCR1, MDFI, PTK2, DHX36, OTUD4, SF3B1, SF3A1, AUP1,
Protein Size: 187

Molekulargewicht: 21 kDa

Gen-ID: 9140

NCBI Accession: NM_004707, NP_004698

UniProt: O94817

Pathways: Autophagie