RABGGTA Antikörper (N-Term)

Produktnummer ABIN2773937

Es sind 2+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-RABGGTA Antikörper wird verwendet zum Nachweis von RABGGTA in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für RABGGTA Antikörper (N-Term) (ABIN2773937)

Target: RABGGTA (Rab Geranylgeranyltransferase, alpha Subunit (RABGGTA))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RABGGTA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RABGGTA Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: RABGGTA Antibody - N-terminal region

Sequenz: ELAFTDSLIT RNFSNYSSWH YRSCLLPQLH PQPDSGPQGR LPEDVLLKEL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RABGGTA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RABGGTA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8109774

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-RABGGTA Antikörper (ABIN2773937)

Arora, Syed, Machhadieh, McKenna, Kowluru: "Rab-geranylgeranyl transferase regulates glucose-stimulated insulin secretion from pancreatic ? cells." in: Islets, Vol. 4, Issue 5, pp. 354-8, (2012) (PubMed).

Lachance, Cartier, Génier, Munger, Germain, Labrecque, Parent: "Regulation of ?2-adrenergic receptor maturation and anterograde trafficking by an interaction with Rab geranylgeranyltransferase: modulation of Rab geranylgeranylation by the receptor." in: The Journal of biological chemistry, Vol. 286, Issue 47, pp. 40802-13, (2011) (PubMed).

Details zu RABGGTA

Target: RABGGTA (Rab Geranylgeranyltransferase, alpha Subunit (RABGGTA))

Andere Bezeichnung: RABGGTA

Hintergrund:

Targeted Subunit: alpha

Background Information: RABGGTA belongs to the protein prenyltransferase subunit alpha family and contains 6 PFTA repeats. RABGGTA catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively.

Gene Name: Rab geranylgeranyltransferase, alpha subunit

Alternative Symbols: PTAR3

Protein Name: Geranylgeranyl transferase type-2 subunit alpha

Molekulargewicht: 65kDa

Gen-ID: 5875

NCBI Accession: NP_878256

UniProt: Q92696