RABGGTA Antikörper (N-Term)

Produktnummer ABIN2773937

Der Kaninchen Polyklonal Anti-RABGGTA-Antikörper wurde für WB validiert. Er ist geeignet, RABGGTA in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für RABGGTA Antikörper (N-Term) (ABIN2773937)

Target: RABGGTA (Rab Geranylgeranyltransferase, alpha Subunit (RABGGTA))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RABGGTA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RABGGTA Antikörper

Bindungsspezifität: N-Term

Sequenz: ELAFTDSLIT RNFSNYSSWH YRSCLLPQLH PQPDSGPQGR LPEDVLLKEL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RABGGTA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RABGGTA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 567 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-RABGGTA Antikörper (ABIN2773937)

Arora, Syed, Machhadieh, McKenna, Kowluru: "Rab-geranylgeranyl transferase regulates glucose-stimulated insulin secretion from pancreatic ? cells." in: Islets, Vol. 4, Issue 5, pp. 354-8, (2012) (PubMed).

Lachance, Cartier, Génier, Munger, Germain, Labrecque, Parent: "Regulation of ?2-adrenergic receptor maturation and anterograde trafficking by an interaction with Rab geranylgeranyltransferase: modulation of Rab geranylgeranylation by the receptor." in: The Journal of biological chemistry, Vol. 286, Issue 47, pp. 40802-13, (2011) (PubMed).

Details zu RABGGTA

Target: RABGGTA (Rab Geranylgeranyltransferase, alpha Subunit (RABGGTA))

Andere Bezeichnung: RABGGTA

Hintergrund: RABGGTA belongs to the protein prenyltransferase subunit alpha family and contains 6 PFTA repeats. RABGGTA catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively.
Alias Symbols: PTAR3
Protein Interaction Partner: UBC, UBA2, VBP1, SSB, PFDN2, RBMXL2, BMPR2, RAB1A,
Protein Size: 567

Molekulargewicht: 65 kDa

Gen-ID: 5875

NCBI Accession: NM_182836, NP_878256

UniProt: Q92696