KREMEN1 Antikörper (N-Term)

Produktnummer ABIN2773853

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch KREMEN1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Meerschweinchen, Kaninchen, Rind (Kuh), Hund und Pferd.

Kurzübersicht für KREMEN1 Antikörper (N-Term) (ABIN2773853)

Target: KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Kaninchen, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KREMEN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KREMEN1 Antikörper

Bindungsspezifität: N-Term

Sequenz: WKYCEIPACQ MPGNLGCYKD HGNPPPLTGT SKTSNKLTIQ TCISFCRSQR

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against KREMEN1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KREMEN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 475 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KREMEN1

Target: KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))

Andere Bezeichnung: KREMEN1

Hintergrund: KREMEN1 is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. It is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains.This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
Alias Symbols: FLJ31863, KREMEM1, KREMEN, KRM1
Protein Interaction Partner: DKK1,
Protein Size: 475

Molekulargewicht: 50 kDa

Gen-ID: 83999

NCBI Accession: NM_001039570, NP_001034659

UniProt: Q96MU8

Pathways: WNT Signalweg