KREMEN1 Antikörper (N-Term)

Produktnummer ABIN2773853

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch KREMEN1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Meerschweinchen, Kaninchen, Rind (Kuh), Hund und Pferd.

Kurzübersicht für KREMEN1 Antikörper (N-Term) (ABIN2773853)

Target: KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Kaninchen, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KREMEN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KREMEN1 Antikörper

Bindungsspezifität: N-Term

Sequenz: WKYCEIPACQ MPGNLGCYKD HGNPPPLTGT SKTSNKLTIQ TCISFCRSQR

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against KREMEN1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KREMEN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 475 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KREMEN1

Target: KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))

Andere Bezeichnung: KREMEN1

Hintergrund: KREMEN1 is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. It is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains.This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
Alias Symbols: FLJ31863, KREMEM1, KREMEN, KRM1
Protein Interaction Partner: DKK1,
Protein Size: 475

Molekulargewicht: 50 kDa

Gen-ID: 83999

NCBI Accession: NM_001039570, NP_001034659

UniProt: Q96MU8

Pathways: WNT Signalweg