ACLY Antikörper (Middle Region)

Produktnummer ABIN2773810

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ACLY in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Schwein, Rind (Kuh), Zebrafisch (Danio rerio), Kaninchen, Schaf, Hund, Pferd und Meerschweinchen.Es wurde in 1 Publikation zitiert.

Kurzübersicht für ACLY Antikörper (Middle Region) (ABIN2773810)

Target: ACLY (ATP Citrate Lyase (ACLY))

Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Zebrafisch (Danio rerio), Kaninchen, Schaf, Hund, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACLY Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ACLY Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: ACLY Antibody - middle region

Sequenz: SRTASFSESR ADEVAPAKKA KPAMPQDSVP SPRSLQGKST TLFSRHTKAI

Homologie: Cow: 92%, Dog: 93%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 93%, Sheep: 92%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against ACLY. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ACLY

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42736-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ACLY Antikörper (ABIN2773810)

Convertini, Menga, Andria, Scala, Santarsiero, Castiglione Morelli, Iacobazzi, Infantino: "The contribution of the citrate pathway to oxidative stress in Down syndrome." in: Immunology, Vol. 149, Issue 4, pp. 423-431, (2016) (PubMed).

Details zu ACLY

Target: ACLY (ATP Citrate Lyase (ACLY))

Andere Bezeichnung: ACLY

Hintergrund:

Background Information: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acety

Gene Name: ATP citrate lyase

Alternative Symbols: ACL, ATPCL, CLATP

Protein Name: ATP-citrate synthase

Molekulargewicht: 121kDa

Gen-ID: 47

NCBI Accession: NP_001087

UniProt: P53396

Pathways: Warburg Effekt