ACLY Antikörper (Middle Region)

Produktnummer ABIN2773810

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ACLY in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Schwein, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Schaf, Hund, Pferd und Meerschweinchen und wurde in 1 Publikation erwähnt.

Kurzübersicht für ACLY Antikörper (Middle Region) (ABIN2773810)

Target: ACLY (ATP Citrate Lyase (ACLY))

Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Schaf, Hund, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACLY Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ACLY Antikörper

Bindungsspezifität: Middle Region

Sequenz: SRTASFSESR ADEVAPAKKA KPAMPQDSVP SPRSLQGKST TLFSRHTKAI

Homologie: Cow: 92%, Dog: 93%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 93%, Sheep: 92%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against ACLY. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ACLY

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1101 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ACLY Antikörper (ABIN2773810)

Convertini, Menga, Andria, Scala, Santarsiero, Castiglione Morelli, Iacobazzi, Infantino: "The contribution of the citrate pathway to oxidative stress in Down syndrome." in: Immunology, Vol. 149, Issue 4, pp. 423-431, (2016) (PubMed).

Details zu ACLY

Target: ACLY (ATP Citrate Lyase (ACLY))

Andere Bezeichnung: ACLY

Hintergrund: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acety
Alias Symbols: ACL, ATPCL, CLATP
Protein Interaction Partner: UBC, UBR4, SIRT2, HUWE1, ISG15, KAT2B, SUMO2, SUMO3, STAU1, SUMO1, NEDD8, MDM2, ASB15, WWOX, TRIM25, MAGED2, BAG3, PPP6C, NCL, MCM6, MCM2, KPNA4, KPNA2, PRMT1, CDKN2A, SRRT, UBD, FN1, APP, SHC1, CUL3, CAND1, CUL2, SIRT7, UL27, HDAC5, TERF2, TERF1, GSK3B,
Protein Size: 1101

Molekulargewicht: 121 kDa

Gen-ID: 47

NCBI Accession: NM_001096, NP_001087

UniProt: P53396

Pathways: Warburg Effekt