AGPS Antikörper (AA 158-384)

Produktnummer ABIN2749041

Der Maus Monoklonal Anti-AGPS-Antikörper wurde für WB und ICFC validiert. Er ist geeignet, AGPS in Proben von Human zu detektieren.

Kurzübersicht für AGPS Antikörper (AA 158-384) (ABIN2749041)

Target: AGPS (Alkylglycerone Phosphate Synthase (AGPS))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser AGPS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Intracellular Flow Cytometry (ICFC)

Klon: AGPS-03

Produktdetails anti-AGPS Antikörper

Bindungsspezifität: AA 158-384

Verwendungszweck: Anti-AGPS Purified

Spezifität: The mouse monoclonal antibody AGPS-03 recognizes AGPS (alkykglycerone phosphate synthase), an intracellular peroxisomal enzyme important for lipid biosynthesis.

Kreuzreaktivität (Details): Human

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: recombinant human AGPS (amino acids 158-384)

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.
Western blotting: Recommended dilution: 1-2 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu AGPS

Target: AGPS (Alkylglycerone Phosphate Synthase (AGPS))

Andere Bezeichnung: AGPS

Hintergrund: Alkylglycerone phosphate synthase,AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse.,ADAS, ADPS, RCDP3, ADAP-S, ADHAPS, ALDHPSY

Gen-ID: 8540

UniProt: O00116

Pathways: SARS-CoV-2 Protein Interaktom