CD2 Antikörper

Produktnummer ABIN2749021

Dieses Anti-CD2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD2 in FACS und Func. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für CD2 Antikörper (ABIN2749021)

Target: CD2

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Functional Studies (Func)

Klon: TS1-8

Produktdetails anti-CD2 Antikörper

Verwendungszweck: Anti-Hu CD2 Purified Low Endotoxin

Spezifität: The mouse monoclonal antibody TS1/8 recognizes an extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells, also expressed by all thymocytes.

Kreuzreaktivität (Details): Human

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Endotoxin-Niveau: Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.

Immunogen: Cytotoxic T lymphocytes

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Functional application: Blocking.
Flow cytometry: Recommended dilution: 1-4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Referenzen für anti-CD2 Antikörper (ABIN2749021)

Zhang, Dai, Li, Zhuang: "Tracking proliferative history in lymphocyte development with cre-mediated sister chromatid recombination." in: PLoS genetics, Vol. 9, Issue 10, pp. e1003887, (2013) (PubMed).

Details zu CD2

Target: CD2

Andere Bezeichnung: CD2

Hintergrund: CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,T11, LFA-2, SRBC

Gen-ID: 914

UniProt: P06729