MERTK Antikörper (C-Mer Proto-Oncogene Tyrosine Kinase) (N-Term)

Details for Product anti-MERTK Antibody No. ABIN2746860, Anbieter: Anmelden zum Anzeigen
Antigen
  • MER
  • RP38
  • c-mer
  • Eyk
  • Mer
  • Nyk
  • nmf12
  • rdy
  • C-EYK
  • MERTK
  • DKFZp469D2215
  • si:ch1073-268l12.2
  • MER proto-oncogene, tyrosine kinase
  • c-mer proto-oncogene tyrosine kinase
  • c-mer proto-oncogene tyrosine kinase a
  • MERTK
  • Mertk
  • mertka
Epitop
N-Term
37
27
15
9
6
5
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
183
95
52
5
2
2
1
1
1
1
1
Wirt
Kaninchen
129
35
31
28
Klonalität
Polyklonal
Konjugat
Dieser MERTK Antikörper ist unkonjugiert
13
11
8
8
7
5
5
5
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Confocal Microscopy (CM), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
146
104
81
35
32
22
17
16
13
12
4
3
2
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Immunogen Synthetic peptide corresponding to unique amino acid sequence on MerTK protein.
Isotyp IgG
Reinigung Affinity Purified
Plasmids, Primers & others Plasmide, Primers & weitere MERTK products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung MERTK (MERTK Antibody Abstract)
UniProt Q12866
Pathways RTK Signalweg
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.75 μg/μL
Produkt verwendet in: Ginisty, Gély-Pernot, Abaamrane, Morel, Arnault, Coronas, Benzakour: "Evidence for a subventricular zone neural stem cell phagocytic activity stimulated by the vitamin K-dependent factor protein S." in: Stem cells (Dayton, Ohio), Vol. 33, Issue 2, pp. 515-25, 2015 (PubMed).

Farkas, Lew, Sousa, Bujakowska, Chatagnon, Bhattacharya, Pierce, Nandrot: "Mutations in pre-mRNA processing factors 3, 8, and 31 cause dysfunction of the retinal pigment epithelium." in: The American journal of pathology, Vol. 184, Issue 10, pp. 2641-52, 2014 (PubMed).

Fraineau, Monvoisin, Clarhaut, Talbot, Simonneau, Kanthou, Kanse, Philippe, Benzakour: "The vitamin K-dependent anticoagulant factor, protein S, inhibits multiple VEGF-A-induced angiogenesis events in a Mer- and SHP2-dependent manner." in: Blood, Vol. 120, Issue 25, pp. 5073-83, 2013 (PubMed).

Choi, Park, Lee, Byun, Youn, Choi, Woo, Kang: "Upregulation of Mer receptor tyrosine kinase signaling attenuated lipopolysaccharide-induced lung inflammation." in: The Journal of pharmacology and experimental therapeutics, Vol. 344, Issue 2, pp. 447-58, 2013 (PubMed).

Qin, Rodrigues: "Roles of αvβ5, FAK and MerTK in oxidative stress inhibition of RPE cell phagocytosis." in: Experimental eye research, Vol. 94, Issue 1, pp. 63-70, 2012 (PubMed).

Lee, Han, Byun, Park, Park, Chong, Cho, Kang: "Inhibiting Mer receptor tyrosine kinase suppresses STAT1, SOCS1/3, and NF-κB activation and enhances inflammatory responses in lipopolysaccharide-induced acute lung injury." in: Journal of leukocyte biology, Vol. 91, Issue 6, pp. 921-32, 2012 (PubMed).

Caberoy, Zhou, Li: "Tubby and tubby-like protein 1 are new MerTK ligands for phagocytosis." in: The EMBO journal, Vol. 29, Issue 23, pp. 3898-910, 2011 (PubMed).

Tibrewal, Wu, Dmello, Akakura, George, Varnum, Birge: "Autophosphorylation docking site Tyr-867 in Mer receptor tyrosine kinase allows for dissociation of multiple signaling pathways for phagocytosis of apoptotic cells and down-modulation of lipopolysaccharide-inducible NF-kappaB transcriptional activation." in: The Journal of biological chemistry, Vol. 283, Issue 6, pp. 3618-27, 2008 (PubMed).

Wu, Singh, Georgescu, Birge: "A role for Mer tyrosine kinase in alphavbeta5 integrin-mediated phagocytosis of apoptotic cells." in: Journal of cell science, Vol. 118, Issue Pt 3, pp. 539-53, 2005 (PubMed).

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