MERTK Antikörper (N-Term)

Produktnummer ABIN2746860

Es sind 9+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-MERTK Antikörper wird verwendet zum Nachweis von MERTK in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, ELISA, IP, IF, ICC und CM.

Kurzübersicht für MERTK Antikörper (N-Term) (ABIN2746860)

Target: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MERTK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Confocal Microscopy (CM)

Produktdetails anti-MERTK Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Affinity Purified

Immunogen: Synthetic peptide corresponding to unique amino acid sequence on MerTK protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.75 μg/μL

Referenzen für anti-MERTK Antikörper (ABIN2746860)

Ginisty, Gély-Pernot, Abaamrane, Morel, Arnault, Coronas, Benzakour: "Evidence for a subventricular zone neural stem cell phagocytic activity stimulated by the vitamin K-dependent factor protein S." in: Stem cells (Dayton, Ohio), Vol. 33, Issue 2, pp. 515-25, (2015) (PubMed).

Farkas, Lew, Sousa, Bujakowska, Chatagnon, Bhattacharya, Pierce, Nandrot: "Mutations in pre-mRNA processing factors 3, 8, and 31 cause dysfunction of the retinal pigment epithelium." in: The American journal of pathology, Vol. 184, Issue 10, pp. 2641-52, (2014) (PubMed).

Fraineau, Monvoisin, Clarhaut, Talbot, Simonneau, Kanthou, Kanse, Philippe, Benzakour: "The vitamin K-dependent anticoagulant factor, protein S, inhibits multiple VEGF-A-induced angiogenesis events in a Mer- and SHP2-dependent manner." in: Blood, Vol. 120, Issue 25, pp. 5073-83, (2013) (PubMed).

Choi, Park, Lee, Byun, Youn, Choi, Woo, Kang: "Upregulation of Mer receptor tyrosine kinase signaling attenuated lipopolysaccharide-induced lung inflammation." in: The Journal of pharmacology and experimental therapeutics, Vol. 344, Issue 2, pp. 447-58, (2013) (PubMed).

Qin, Rodrigues: "Roles of αvβ5, FAK and MerTK in oxidative stress inhibition of RPE cell phagocytosis." in: Experimental eye research, Vol. 94, Issue 1, pp. 63-70, (2012) (PubMed).

Lee, Han, Byun, Park, Park, Chong, Cho, Kang: "Inhibiting Mer receptor tyrosine kinase suppresses STAT1, SOCS1/3, and NF-κB activation and enhances inflammatory responses in lipopolysaccharide-induced acute lung injury." in: Journal of leukocyte biology, Vol. 91, Issue 6, pp. 921-32, (2012) (PubMed).

Caberoy, Zhou, Li: "Tubby and tubby-like protein 1 are new MerTK ligands for phagocytosis." in: The EMBO journal, Vol. 29, Issue 23, pp. 3898-910, (2011) (PubMed).

Tibrewal, Wu, Dmello, Akakura, George, Varnum, Birge: "Autophosphorylation docking site Tyr-867 in Mer receptor tyrosine kinase allows for dissociation of multiple signaling pathways for phagocytosis of apoptotic cells and down-modulation of lipopolysaccharide-inducible NF-kappaB transcriptional activation." in: The Journal of biological chemistry, Vol. 283, Issue 6, pp. 3618-27, (2008) (PubMed).

Wu, Singh, Georgescu, Birge: "A role for Mer tyrosine kinase in alphavbeta5 integrin-mediated phagocytosis of apoptotic cells." in: Journal of cell science, Vol. 118, Issue Pt 3, pp. 539-53, (2005) (PubMed).

Details zu MERTK

Target: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Andere Bezeichnung: MERTK

UniProt: Q12866

Pathways: RTK Signalweg