G0S2 Antikörper

Produktnummer ABIN2746830

Der Kaninchen Polyklonal Anti-G0S2-Antikörper wurde für WB, ELISA und IP validiert. Er ist geeignet, G0S2 in Proben von Human, Maus, Affe und Ratte zu detektieren.

Kurzübersicht für G0S2 Antikörper (ABIN2746830)

Target: G0S2 (G0/G1switch 2 (G0S2))

Reaktivität: Human, Maus, Affe, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser G0S2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Produktdetails anti-G0S2 Antikörper

Kreuzreaktivität: Ratte (Rattus), Maus, Affe

Produktmerkmale: The G0S2-specific antibodies were generated using synthetic peptide derived from the from the C-terminal region of the G0S2 protein from within the region spanning AA 79-103. The G0S2-specific antibodies were affinity purified over immobilized antigen based affinity chromatography, and the purified immunoglobulins are stabilized in antibody stabilization buffer for long-term storage.

Aufreinigung: Affinity Purified

Immunogen: Synthetic peptide corresponding to unique amino acid sequences on G0S2 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Antibody was tested in ELISA and western blotting applications at 1:500 dilution using ABIN1040787 samples. Antibody dilutions for this antibody is for reference only, investigators are expected to determine the optimalconditions. Application of this antibody in other protocols has not yet tested.
WB: > 1:500
IMM & IP pull-down assays: n.d.
IHC: n.d.
Investigators using this antibody in protocols other than listed above can request acomplimentary sample of this antibody.
This antibody detects a band of 13 kDa in ABIN1040787 samples.The antibody also reacts to a 13 kDa protein in fat cells and TNF alpha induced THP cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.51-0.54 μg/μL

Buffer: The antiserum is supplied in antibody stabilization buffer with 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Storage of very dilute antibody solutions is not recommended.

Details zu G0S2

Target: G0S2 (G0/G1switch 2 (G0S2))

Andere Bezeichnung: G0/G1 Switch 2

Hintergrund: Lipolysis is the biochemical pathway responsible for the catabolism of triacylglycerol (TAG) stored in cellular lipid droplets by essential TAG hydrolase named adipose triglyceride lipase (ATGL). The ATGL action generates non-esterified fatty acids, which are subsequently used as energy substrate, essential precursors for lipid and membrane synthesis and mediator of cell signaling molecules. ATGL activity is regulated by several enzymes and binding factors including ATGL activator patatin-like phospholipase domain containing protein 58 (alpha/beta hydrolase containing protein 5) and ATGL inhibitor G0/G1 switch gene 2 (G0S2). Other factors/enzymes include hormone sensitive lipase E, and mono glyceride lipase constitute the basic \\

UniProt: Q68515

Pathways: Regulation of Lipid Metabolism by PPARalpha