Podoplanin Antikörper
Kurzübersicht für Podoplanin Antikörper (ABIN2745557)
Target
Alle Podoplanin (PDPN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Recognizes mouse podoplanin.
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Kreuzreaktivität
- Maus
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Keine Kreuzreaktivität
- Human
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Kreuzreaktivität (Details)
- Does not cross-react with human podoplanin.
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Aufreinigung
- Protein G purified.
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Immunogen
- Murine thymic stromal cell line.
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Centrifuge vial prior to opening. Reconstitute with sterile water to a concentration of 0.1-1.0 mg/mL.
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Konzentration
- Lot specific
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Buffer
- Lyophilized.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. -
Haltbarkeit
- 6 months
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- Podoplanin (PDPN)
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Andere Bezeichnung
- Podoplanin
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Hintergrund
- Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma and brain tumors. Podoplanin is the ligand for C-type lectin-like receptor 2 (CLEC-2). Their association is dependent on sialic acid on O-glycans of podoplanin. Through its association with CLEC-2, podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.
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Pathways
- Dicarboxylic Acid Transport
Target
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