Podoplanin Antikörper

Produktnummer ABIN2745557

Dieser Hamster Monoklonal Antikörper detektiert spezifisch Podoplanin in WB, IHC, ELISA und IP. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für Podoplanin Antikörper (ABIN2745557)

Target: Podoplanin (PDPN)

Reaktivität: Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser Podoplanin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Klon: RTD4E10

Produktdetails anti-Podoplanin Antikörper

Verwendungszweck: anti-Podoplanin (mouse), mAb (RTD4E10)

Spezifität: Recognizes mouse podoplanin. Does not cross-react with human podoplanin.

Keine Kreuzreaktivität: Human

Kreuzreaktivität (Details): Does not cross-react with human podoplanin.

Produktmerkmale: Monoclonal Antibody. Recognizes mouse podoplanin. Does not cross-react with human podoplanin. Isotype: Hamster IgG. Clone: RTD4E10. Applications: ELISA, IHC, IP, WB. Lyophilized. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma and brain tumors. Podoplanin is the ligand for C-type lectin-like receptor 2 (CLEC-2). Their association is dependent on sialic acid on O-glycans of podoplanin. Through its association with CLEC-2, podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.

Aufreinigung: Protein G purified.

Immunogen: Murine thymic stromal cell line.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge vial prior to opening. Reconstitute with sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: Lyophilized.

Handhabung: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

+4°C

-20°C

Stable for at least 6 months after receipt when stored at -20°C.

Haltbarkeit: 6 months

Details zu Podoplanin

Target: Podoplanin (PDPN)

Andere Bezeichnung: Podoplanin

Hintergrund:

Alternate Names/Synonyms: Glycoprotein 36, PA2.26 Antigen, Aggrus

Product Description: Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma and brain tumors. Podoplanin is the ligand for C-type lectin-like receptor 2 (CLEC-2). Their association is dependent on sialic acid on O-glycans of podoplanin. Through its association with CLEC-2, podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.

Pathways: Dicarboxylic Acid Transport