Caspase 4 Antikörper
Kurzübersicht für Caspase 4 Antikörper (ABIN2745523)
Target
Alle Caspase 4 (CASP4) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Recognizes mouse and rat full-length caspase-11 protein. Detects two bands of ~38 kDa and ~43 kDa by Western blot.
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Kreuzreaktivität
- Maus, Ratte (Rattus)
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Reinheit
- >95 % (SDS-PAGE)
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Endotoxin-Niveau
- <0.1EU/μg purified protein (LAL test, Lonza).
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Immunogen
- Recombinant mouse caspase-11 (p20 fragment).
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Isotyp
- IgG1
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anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (AA 1-377) antibody
CASP4 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 7G7 unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (AA 290-377) antibodyCASP4 Reaktivität: Human WB, ELISA, ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (AA 82-226) antibodyCASP4 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibodyCASP4 Reaktivität: Maus, Ratte WB, ELISA, IP, FACS Wirt: Ratte Monoclonal 8A5 unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibodyCASP4 Reaktivität: Human WB Wirt: Maus Monoclonal B25-1 unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (cleaved), (Internal Region) antibodyCASP4 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (AA 78-265) antibodyCASP4 Reaktivität: Human WB, ELISA, ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (AA 81-270) antibodyCASP4 Reaktivität: Rind (Kuh) WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (Internal Region) antibodyVerified CASP4 Reaktivität: Human WB, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (AA 111-194) antibodyCASP4 Reaktivität: Human WB, IHC, ELISA, ICC, IF, FACS Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- In PBS containing 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
Haltbarkeit
- 12 months
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- Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
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Andere Bezeichnung
- Caspase-11
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Hintergrund
- Caspase-11 not only activates caspase-1, that is required for the maturation of proinflammatory cytokines such as interleukin-1 (IL-1) and interleukin-18 (IL-18), but also activates caspase-3, leading to cellular apoptosis under pathological conditions. In most cells, caspase-11 is only expressed upon induction with pro-inflammatory stimuli. Caspase-11 is an essential mediator of endotoxic shock and caspase-11-deficient mice are resistant to endotoxic shock. LPS-induced caspase-11 regulates lymphocyte apoptosis by activating both caspase-3 and caspase-7.
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UniProt
- P70343
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
Target
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