BMF Antikörper

Produktnummer ABIN2745518

Dieser Ratte Monoklonal Antikörper erkennt spezifisch BMF in WB, FACS und IP. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für BMF Antikörper (ABIN2745518)

Target: BMF (Bcl2 Modifying Factor (BMF))

Reaktivität: Human, Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser BMF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Klon: 9G10

Produktdetails anti-BMF Antikörper

Spezifität: Recognizes human and mouse Bmf.

Kreuzreaktivität: Human, Maus

Kreuzreaktivität (Details): Detects several cross-reactivity bands of unknown identity in mice by western blot.

Reinheit: >95 % (SDS-PAGE)

Endotoxin-Niveau: <0.1EU/μg purified protein (LAL test, Lonza).

Immunogen: Recombinant mouse Bmf.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: In PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit: 12 months

Details zu BMF

Target: BMF (Bcl2 Modifying Factor (BMF))

Andere Bezeichnung: Bmf

Hintergrund: Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.

UniProt: Q96LC9