APAF1 Antikörper (N-Term)
Kurzübersicht für APAF1 Antikörper (N-Term) (ABIN2745509)
Target
Alle APAF1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-97, N-Term
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Spezifität
- Recognizes the CARD domain of mouse and rat Apaf-1.
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Kreuzreaktivität
- Maus, Ratte (Rattus)
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Keine Kreuzreaktivität
- Human
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Kreuzreaktivität (Details)
- Does not cross-react with human Apaf-1.
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Reinheit
- >95 % (SDS-PAGE)
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Endotoxin-Niveau
- <0.1EU/μg purified protein (LAL test, Lonza).
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Immunogen
- Recombinant mouse Apaf-1 (aa 1-97) containing the N-terminal CARD domain.
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Isotyp
- IgG2a
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anti-Apoptotic Peptidase Activating Factor 1 (APAF1) (AA 1-250) antibody
APAF1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Apoptotic Peptidase Activating Factor 1 (APAF1) (AA 31-350) antibodyAPAF1 Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Apoptotic Peptidase Activating Factor 1 (APAF1) (AA 1138-1237) antibodyAPAF1 Reaktivität: Human ELISA, ICC, FACS Wirt: Maus Monoclonal 2H9A1 unconjugated
anti-Apoptotic Peptidase Activating Factor 1 (APAF1) (C-Term) antibodyAPAF1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Apoptotic Peptidase Activating Factor 1 (APAF1) (AA 1201-1248) antibodyAPAF1 Reaktivität: Human, Ratte, Zebrafisch (Danio rerio) WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Apoptotic Peptidase Activating Factor 1 (APAF1) (AA 13-80) antibodyAPAF1 Reaktivität: Human, Maus, Ratte ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Apoptotic Peptidase Activating Factor 1 (APAF1) (AA 104-415) antibodyAPAF1 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Apoptotic Peptidase Activating Factor 1 (APAF1) (Internal Region) antibodyAPAF1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Apoptotic Peptidase Activating Factor 1 (APAF1) (AA 1-1205) antibodyAPAF1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Apoptotic Peptidase Activating Factor 1 (APAF1) (C-Term) antibodyAPAF1 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- In PBS containing 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
Haltbarkeit
- 12 months
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- APAF1 (Apoptotic Peptidase Activating Factor 1 (APAF1))
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Andere Bezeichnung
- Apaf-1
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Hintergrund
- Apaf-1 is a cytoplasmic protein that forms one of the central hubs in the apoptosis regulatory network. It contains (from the N terminal) a caspase recruitment domain (CARD), an ATPase domain (NB-ARC), few short helical domains and then several copies of the WD40 repeat domain. Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome, mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis.
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UniProt
- Q9EPV5
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Pathways
- p53 Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Tube Formation, Positive Regulation of Endopeptidase Activity
Target
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