Retinol-Binding Protein Antikörper

Produktnummer ABIN2743999

Produktdetails anti-Retinol-Binding Protein Antikörper

Target: Retinol-Binding Protein (RBP)

Reaktivität: Human, Maus, Ziege, Affe, Ratte, Kaninchen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Retinol-Binding Protein Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)

Spezifität: Human RBP / Retinol Binding Protein

Aufreinigung: Protein G purified

Immunogen: Retinol binding protein purified from human plasma.

Type of Immunogen: Purified protein

Klon: G4E4

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, IF (1 - 2 μg/mL), IHC, IHC-Fr (1 - 2 μg/mL), IHC-P (1 - 2 μg/mL), IP, WB (0.5 - 1 μg/mL)

Usage: This antibody recognizes a protein of 21  kDa-25  kDa, identified as retinol binding protein (RBP). Its epitope localizes between amino acids 74-182. The RBP antibody recognizes reduced and carboxy-methylated RBP as well as the circulatory RBP but not the native form, thereby suggesting that its epitope becomes accessible either on unfolding or upon binding of RBP to transthyretin (prealbumin). Retinol binding protein is responsible for distributing retinol from the retinoid stores in the liver to the various target tissues. Once secreted into the blood with bound retinol, the vitamin carrier circulates complexed with transthyretin prior to vitamin delivery at the plasma membrane through a receptor-mediated mechanism. ELISA: Order BSA-free antibody format for coating.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2°C to 8°C.

Details zu Retinol-Binding Protein

Target: Retinol-Binding Protein (RBP)

Andere Bezeichnung: RBP / Retinol Binding Protein (RBP Produkte)

Hintergrund: Name/Gene ID: RBP

Synonyms: RBP