SOCS3 Antikörper
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- Target Alle SOCS3 Antikörper anzeigen
- SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser SOCS3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Produktmerkmale
- Homo sapiens suppressor of cytokine signaling 3 (SOCS3)
- Aufreinigung
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of human SOCS3(NP_003946) produced in HEK293T cell.
- Klon
- 5C2
- Isotyp
- IgG2a
- Top Product
- Discover our top product SOCS3 Primärantikörper
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- Applikationshinweise
- WB 1:2000, IF 1:100,
- Kommentare
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The concentration of the product may vary between diferrent lots.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))
- Andere Bezeichnung
- SOCS3 (SOCS3 Produkte)
- Hintergrund
- This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
- Molekulargewicht
- 24.6 kDa
- Gen-ID
- 9021
- NCBI Accession
- NM_003955
- HGNC
- 9021
- Pathways
- JAK-STAT Signalweg, Response to Growth Hormone Stimulus, Hepatitis C
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