RASSF1 Antikörper
-
- Target Alle RASSF1 Antikörper anzeigen
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser RASSF1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Produktmerkmale
- Homo sapiens Ras association (RalGDS/AF-6) domain family member 1 (RASSF1), transcript variant A
- Aufreinigung
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of human RASSF1 (NP_009113) produced in E.coli.
- Klon
- 2B11
- Isotyp
- IgG1
- Top Product
- Discover our top product RASSF1 Primärantikörper
-
-
- Applikationshinweise
- WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
- Kommentare
-
The concentration of the product may vary between diferrent lots.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
-
- Target
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
- Andere Bezeichnung
- RASSF1 (RASSF1 Produkte)
- Hintergrund
- This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
- Molekulargewicht
- 38.6 kDa
- Gen-ID
- 11186
- NCBI Accession
- NM_007182
- HGNC
- 28844
-