RAMP2 Antikörper
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- Target Alle RAMP2 Antikörper anzeigen
- RAMP2 (Receptor (G Protein-Coupled) Activity Modifying Protein 2 (RAMP2))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser RAMP2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Produktmerkmale
- Homo sapiens receptor (G protein-coupled) activity modifying protein 2 (RAMP2)
- Aufreinigung
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinat protein of human RAMP2(NP_005845) produced in HEK293T cell.
- Klon
- 4E5
- Isotyp
- IgG1
- Top Product
- Discover our top product RAMP2 Primärantikörper
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- Applikationshinweise
- WB 1:1000, IHC 1:150, FLOW 1:100,
- Kommentare
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The concentration of the product may vary between diferrent lots.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- RAMP2 (Receptor (G Protein-Coupled) Activity Modifying Protein 2 (RAMP2))
- Andere Bezeichnung
- RAMP2 (RAMP2 Produkte)
- Hintergrund
- The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface.
- Molekulargewicht
- 15.8 kDa
- Gen-ID
- 10266
- NCBI Accession
- NM_005854
- HGNC
- 10266
- Pathways
- cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling
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