GDF15 Antikörper
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- Target Alle GDF15 Antikörper anzeigen
- GDF15 (Growth Differentiation Factor 15 (GDF15))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser GDF15 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)
- Produktmerkmale
- Homo sapiens peptide deformylase (mitochondrial) (PDF), nuclear gene encoding mitochondrial protein
- Aufreinigung
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of human PDF (NP_071736) produced in HEK293T cell.
- Klon
- 3C12
- Isotyp
- IgG1
- Top Product
- Discover our top product GDF15 Primärantikörper
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anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibody
Verified GDF15 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Ziege Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 51-79) antibodyGDF15 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 30-308) antibodyGDF15 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 221-308) antibodyGDF15 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 51-79), (N-Term) antibodyGDF15 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB30209 unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibody (Biotin)GDF15 Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal Biotin
anti-Growth Differentiation Factor 15 (GDF15) (AA 195-308) antibodyGDF15 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 198-308) antibodyGDF15 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 16-143) antibodyGDF15 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (N-Term) antibodyGDF15 Reaktivität: Human WB, ELISA, IHC, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500, IF 1:100, FLOW 1:100
- Kommentare
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The concentration of the product may vary between diferrent lots.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- GDF15 (Growth Differentiation Factor 15 (GDF15))
- Andere Bezeichnung
- PDF (GDF15 Produkte)
- Hintergrund
- Protein synthesis proceeds after formylation of methionine by methionyl-tRNA formyl transferase (FMT) and transfer of the charged initiator f-met tRNA to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of nascent peptides. In eubacteria, deformylation of nascent peptides is required for subsequent cleavage of initiating methionines by methionine aminopeptidase. The discovery that a natural inhibitor of PDF, actinonin, acts as an antimicrobial agent in some bacteria has spurred intensive research into the design of bacterial-specific PDF inhibitors. In human cells, only mitochondrial proteins have N-formylation of initiating methionines. Protein inhibitors of PDF or siRNAs of PDF block the growth of cancer cell lines but have no effect on normal cell growth. In humans, PDF function may therefore be restricted to rapidly growing cells.
- Molekulargewicht
- 19.4 kDa
- Gen-ID
- 64146
- NCBI Accession
- NM_022341
- HGNC
- 64146
- Pathways
- SARS-CoV-2 Protein Interaktom
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