CD2 Antikörper (PE)

Produktnummer ABIN272342

Der Maus Monoklonal Anti-CD2 Antikörper wurde für FACS validiert. Er ist geeignet, CD2 in Proben von Human zu detektieren.

Kurzübersicht für CD2 Antikörper (PE) (ABIN272342)

Target: CD2

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD2 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: MEM-65

Produktdetails anti-CD2 Antikörper (PE)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry analysis of blood cells using 20 m l reagent / 100 m l of whole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C. DO NOT FREEZE! Centrifuge vial before opening. This product is photosensitive and should be protected from light.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD2

Target: CD2

Andere Bezeichnung: CD2

Hintergrund: CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Morover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.Synonyms: Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, SRBC, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5

UniProt: P06729