N-Cadherin Antikörper
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- Target Alle N-Cadherin (CDH2) Antikörper anzeigen
- N-Cadherin (CDH2) (Cadherin 2 (CDH2))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser N-Cadherin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody detects endogenous levels of N-cadherin protein. (region surrounding Trp745)
- Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- Reinheit
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product CDH2 Primärantikörper
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- Applikationshinweise
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- DO NOT FREEZE!
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C.
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- Target
- N-Cadherin (CDH2) (Cadherin 2 (CDH2))
- Andere Bezeichnung
- Cadherin-2 (CDH2 Produkte)
- Synonyme
- CD325 antikoerper, CDHN antikoerper, CDw325 antikoerper, NCAD antikoerper, N-cadherin antikoerper, cadherin-2 antikoerper, cdhn antikoerper, ncad antikoerper, cdw325 antikoerper, CDH2 antikoerper, Cadherin-2 antikoerper, Ncad antikoerper, glo antikoerper, lyr antikoerper, pac antikoerper, wu:fb47h04 antikoerper, cadherin 2 antikoerper, cadherin 2 S homeolog antikoerper, cadherin 2, type 1, N-cadherin (neuronal) antikoerper, CDH2 antikoerper, cdh2.S antikoerper, cdh2 antikoerper, Cdh2 antikoerper
- Hintergrund
- Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2-terminal repeats. The most distal of these cadherins is thought to be responsible for binding specificity, transmembrane domains and carboxyterminal intracellular domains. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as β-catenin, to regulate cadherin function. Members of this family of adhesion proteins include rat cadherin K (and its human homolog, cadherin-6), R-cadherin, B-cadherin, E/P-cadherin and cadherin-5.Synonyms: CDH2, CDHN, CDw325, Cadherin N, N-Cadherin, NCAD, Neural cadherin
- Molekulargewicht
- approx. 100, 140 kDa
- Gen-ID
- 1000
- NCBI Accession
- NP_001783
- UniProt
- P19022
- Pathways
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane
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