alpha 1 Adrenergic Receptor Antikörper

Produktnummer ABIN272286

Der Kaninchen Polyklonal anti-alpha 1 Adrenergic Receptor Antikörper (ABIN272286) detektiert spezifisch alpha 1 Adrenergic Receptor in WB, IF und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für alpha 1 Adrenergic Receptor Antikörper (ABIN272286)

Target: alpha 1 Adrenergic Receptor (ADRA1A) (Adrenoceptor alpha 1A (ADRA1A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser alpha 1 Adrenergic Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-alpha 1 Adrenergic Receptor Antikörper

Spezifität: This antibody detects endogenous levels of AR-alpha1A protein. (region surrounding Gln365)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse, Rat.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu alpha 1 Adrenergic Receptor

Target: alpha 1 Adrenergic Receptor (ADRA1A) (Adrenoceptor alpha 1A (ADRA1A))

Andere Bezeichnung: alpha-1A Adrenergic Receptor

Hintergrund: Alpha1A-adrenergic receptors (alpha1A-ARs) mediate actions in the sympathetic nervous system through the binding of the catecholamines, epinephrine and norepinephrine. alpha1A-AR couples to Gq/11 and regulates blood pressure due to changes in vascular tone and cardiac output. Alternative splicing of the ADRA1A gene generates four isoforms with distinct C-termini, and the different expression profile of these subtypes produces distinct patterns of activation. alpha1A-AR transcripts are abundant in heart, brain, liver and prostate. alpha1A-AR transcript sizes of 6.0, 4.0, 3.0, and 2.0 kb have been detected in liver. Transcripts of 6.0, 4.0 and 3.0 kb have been detected in heart, and transcripts of 6.0 and 4.0 kb have been detected in prostate.Synonyms: ADRA1A, ADRA1C, Alpha 1A-adrenoceptor, Alpha 1A-adrenoreceptor, Alpha-1C adrenergic receptor, Alpha-adrenergic receptor 1c

Molekulargewicht: approx. 51 kDa

Gen-ID: 148

NCBI Accession: NP_000671

UniProt: P35348

Pathways: AMPK Signaling