MKNK1 Antikörper

Produktnummer ABIN272252

Produktdetails anti-MKNK1 Antikörper

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MKNK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of Mnk1 protein. (region surrounding Ile136)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu MKNK1

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Andere Bezeichnung: MKNK1 (MKNK1 Produkte)

Synonyme: MNK1 antikoerper, MKNK1 antikoerper, zgc:171912 antikoerper, 2410048M24Rik antikoerper, Mnk1 antikoerper, MAPK signal-integrating kinase 1 antikoerper, mknk1 antikoerper, mnk1 antikoerper, MAP kinase interacting serine/threonine kinase 1 antikoerper, MAP kinase-interacting serine/threonine kinase 1 antikoerper, MAP kinase interacting serine/threonine kinase 1 S homeolog antikoerper, MKNK1 antikoerper, mknk1 antikoerper, Mknk1 antikoerper, mknk1.S antikoerper

Hintergrund: The MAPKAP kinases (for MAP kinase activated protein kinases) are a group of MAP kinase substrates which are themselves kinases. In response to activation, the MAP kinases phosphorylate downstream components on a consensus Pro-X-Ser/Thr-Pro motif. Several kinases that contain this motif have been identifed and serve as substrates for the ERK and p38 MAP kinases. These include the serine/threonine kinases Rsk-1 (also designated MAPKAP kinase-1), Rsk-2 and Rsk-3, which are phosphorylated by ERK1 and ERK2. Similarly p38 phosphorylates and activates the serine/threonine kinases MAPKAP kinase-2 and MAPKAP kinase-3 (also designated 3pK). The serine/threonine kinases Mnk1 and Mnk2 are substrates for both ERK and p38 MAP kinases.Synonyms: MAP kinase-interacting serine/threonine-protein kinase 1, MNK1

Molekulargewicht: approx. 51 kDa

Gen-ID: 8569

NCBI Accession: NP_001129025

UniProt: Q9BUB5

Pathways: MAPK Signalweg, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor