E2F2 Antikörper
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- Target Alle E2F2 Antikörper anzeigen
- E2F2 (E2F Transcription Factor 2 (E2F2))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser E2F2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- This antibody detects endogenous levels of E2F-2 protein. (region surrounding Lys236)
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- Reinheit
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product E2F2 Primärantikörper
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- Applikationshinweise
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ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- DO NOT FREEZE!
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C.
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- Target
- E2F2 (E2F Transcription Factor 2 (E2F2))
- Andere Bezeichnung
- E2F2 (E2F2 Produkte)
- Synonyme
- E2F-2 antikoerper, CG1071 antikoerper, Dmel\\CG1071 antikoerper, E2F antikoerper, E2F2 antikoerper, dE2F-2 antikoerper, dE2F2 antikoerper, dE2f2 antikoerper, de2f2 antikoerper, e2f2 antikoerper, 9230110J10 antikoerper, E130207A07 antikoerper, fb40b03 antikoerper, wu:fb40b03 antikoerper, E2F transcription factor 2 antikoerper, si:ch211-160f23.5 antikoerper, E2F2 antikoerper, E2f2 antikoerper, si:ch211-160f23.5 antikoerper
- Hintergrund
- The human retinoblastoma gene product appears to play an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus-encoded proteins. Of all the Rb associations described to date, the identification of a complex between Rb and the transcription factor E2F most directly implicates Rb in regulation of cell proliferation. E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1 and S phases of the cell cycle. E2F-1 is a member of a broader family of transcription regulators including E2F-2, E2F-3, E2F-4, E2F-5 and E2F-6, each of which forms heterodimers with a second protein, DP-1, forming an active E2F transcriptional regulatory complex.Synonyms: E2F transcription factor 2, E2F-2, Transcription factor E2F2
- Molekulargewicht
- approx. 48 kDa
- Gen-ID
- 1870
- NCBI Accession
- NP_004082
- UniProt
- Q14209
- Pathways
- Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication
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