CEBPB Antikörper

Produktnummer ABIN272175

Produktdetails anti-CEBPB Antikörper

Target: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CEBPB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of C/EBP-β protein. (region surrounding Val259)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 1000approx. 1: 5000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 15 mM Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CEBPB

Target: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Andere Bezeichnung: CEBPB (CEBPB Produkte)

Synonyme: C/EBPbeta antikoerper, c/ebp-beta antikoerper, crp2 antikoerper, il6dbp antikoerper, lap antikoerper, nf-il6 antikoerper, tcf5 antikoerper, xC/EBPbeta antikoerper, cebpbb antikoerper, cb380 antikoerper, c/ebpb antikoerper, fe11e05 antikoerper, wu:fe11e05 antikoerper, CEBPB antikoerper, LOC100136165 antikoerper, C/EBP-beta antikoerper, CRP2 antikoerper, IL6DBP antikoerper, LAP antikoerper, NF-IL6 antikoerper, TCF5 antikoerper, IL-6DBP antikoerper, LIP antikoerper, NF-M antikoerper, Nfil6 antikoerper, Il6dbp antikoerper, CCAAT/enhancer binding protein beta antikoerper, CCAAT/enhancer binding protein beta L homeolog antikoerper, CCAAT/enhancer binding protein (C/EBP), beta antikoerper, CCAAT/enhancer-binding protein beta antikoerper, cebpb antikoerper, cebpb.L antikoerper, CEBPB antikoerper, LOC100136165 antikoerper, Cebpb antikoerper

Hintergrund: C/EBP β is a member of the C/EBP transcription factor family. The C/EBP β gene encodes several isoforms, which have truncated transcription activation domains by the alternative translational initiation at multipe AUG start sites. Initiation of translation at the in-frame AUGs forms four C/EBP β isoforms. C/EBP β is also known as interleukin 6-dependent DNA-binding protein (IL6DBP), liver activator protein(LAP) or liver-enriched transcriptional activator protein transcription factor 5 (TCF5). C/EBP β contributes to the regulation of the acute phase response in hepatocytes. Stat3 has an important function in IL-6-mediated transcription of the C/EBP β gene that has direct implication for acute phase response in liver cells.The 35 kDa C/EBP β form requires phosphorylation for its DNA binding ability, and increased binding of C/EBP β isoforms during acute-phase reaction occurs through its upregulation and structural modification.Synonyms: C/EBP beta, CCAAT/enhancer-binding protein beta, LAP, Liver activator protein, NF-IL6, Nuclear factor NF-IL6, TCF5, Transcription factor 5

Molekulargewicht: approx. 36 kDa

Gen-ID: 1051

NCBI Accession: NP_005185

UniProt: P17676

Pathways: Interferon-gamma Pathway, Autophagie, Brown Fat Cell Differentiation