TPT1 Antikörper

Produktnummer ABIN272165

Produktdetails anti-TPT1 Antikörper

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of HRF protein. (region surrounding Lys100)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu TPT1

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Andere Bezeichnung: TPT1 / TCTP (TPT1 Produkte)

Synonyme: HRF antikoerper, TCTP antikoerper, p02 antikoerper, Trt antikoerper, p21 antikoerper, p23 antikoerper, TPT1 antikoerper, TCT1 antikoerper, tctp antikoerper, fa28a02 antikoerper, id:ibd2078 antikoerper, wu:fa28a02 antikoerper, PCHK23 antikoerper, hrf antikoerper, MGC79720 antikoerper, Tpt1 antikoerper, translationally controlled tumor protein antikoerper, CG4800 antikoerper, Dmel\\CG4800 antikoerper, dTCTP antikoerper, Tctp antikoerper, tumor protein, translationally-controlled 1 antikoerper, tumor protein, translationally-controlled 1 L homeolog antikoerper, translationally-controlled tumor protein antikoerper, translationally controlled tumor protein antikoerper, translationally controlled tumor-like protein antikoerper, Translationally controlled tumor protein antikoerper, translationally-controlled tumor protein homolog antikoerper, P23 tumor protein-like antikoerper, TPT1 antikoerper, Tpt1 antikoerper, tpt1 antikoerper, tpt1.L antikoerper, LOC711798 antikoerper, TCTP antikoerper, LOC548038 antikoerper, Tctp antikoerper, LOC108708523 antikoerper, LOC109404863 antikoerper, LOC105389397 antikoerper, LOC102577554 antikoerper

Hintergrund: Histamine is an inflammatory mediator that is ubiquitously expressed and has a broad range of pharmacologic effects. Specifically, it plays a role in the central nervous, gastrointestinal, respiratory and immune systems. Histamine release is mediated by the stimulation of mast cells and basophils. Histamine-releasing factor (HRF) is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. HRF belongs to the translationally controlled tumor protein (TCTP) family and is detected as a protein of 21 kDa in mice and 23 kDa in human. It is expressed in several healthy and tumoral cells, including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas and lymphomas, and it is localized in the cytoplasm. HRF plays a pivotal role in allergic diseases, and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down Syndrome.Synonyms: Fortilin, HRF, Histamine-releasing factor, Translationally-controlled tumor protein

Molekulargewicht: approx. 24 kDa

Gen-ID: 7178

NCBI Accession: NP_003286

UniProt: P13693

Pathways: Response to Water Deprivation, Regulation of Cell Size, Negative Regulation of intrinsic apoptotic Signaling