Ephrin B1 Antikörper

Produktnummer ABIN271886

Produktdetails anti-Ephrin B1 Antikörper

Target: Ephrin B1 (EFNB1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ephrin B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of Ephrin-B protein. (region surrounding Gln324)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Also reacts to: Ephrin-B2

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Ephrin B1

Target: Ephrin B1 (EFNB1)

Andere Bezeichnung: Ephrin-B1 (EFNB1 Produkte)

Synonyme: EFNB1 antikoerper, LERK2 antikoerper, Cek5-L antikoerper, EFL-3 antikoerper, Elk-L antikoerper, Epl2 antikoerper, Eplg2 antikoerper, LERK-2 antikoerper, Lerk2 antikoerper, Stra1 antikoerper, CFND antikoerper, CFNS antikoerper, EFL3 antikoerper, EPLG2 antikoerper, cfnd antikoerper, cfns antikoerper, efl3 antikoerper, efnb1-A antikoerper, ephrinB1 antikoerper, eplg2 antikoerper, lerk2 antikoerper, ephrin B1 antikoerper, ephrin-B1 antikoerper, ephrin-B1 L homeolog antikoerper, EFNB1 antikoerper, Efnb1 antikoerper, efnb1 antikoerper, efnb1.L antikoerper

Hintergrund: Ephrins, which act as ligands for Eph receptors, are cell-surface proteins which fall into two categories, ephrin-A and ephrin-B based on their structure and function. Ephrin-B proteins are transmembrane and have conserved cytoplasmic tyrosine residues that are phosphorylated upon interaction with an EphB receptor. Eph receptors and ephrins exhibit complementary expression in many tissues during embryogenesis indicating that bidirectional activation of Eph receptors and ephrin-B proteins may occur at expression domain interfaces. Ephrin-B1 transduces outside-in signals through C-terminal protein interactions that effect integrin-mediated cell attachment and migration. The distribution of ephrin-B1 in the developing retina suggests that it influences retinal axon mapping along the dorsal-ventral axis and may be involved in intratectal development.Synonyms: CEK5 LIgand, CEK5-L, EFL-3, EFL3, EFNB1, ELK-L, EPH-related receptor tyrosine kinase ligand 2, EPLG2, LERK-2, LERK2

Molekulargewicht: approx. 59 kDa

Gen-ID: 1947

NCBI Accession: NP_004420

UniProt: P98172

Pathways: RTK Signalweg