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FGFR2 Antikörper

Der Maus Monoklonal Anti-FGFR2-Antikörper wurde für WB, FACS und IF validiert. Er ist geeignet, FGFR2 in Proben von Human zu detektieren.
Produktnummer ABIN2717921

Kurzübersicht für FGFR2 Antikörper (ABIN2717921)

Target

Alle FGFR2 Antikörper anzeigen
FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

Reaktivität

  • 129
  • 59
  • 53
  • 11
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 115
  • 14
  • 2
  • 1
Maus

Klonalität

  • 104
  • 28
Monoklonal

Konjugat

  • 74
  • 9
  • 7
  • 5
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FGFR2 Antikörper ist unkonjugiert

Applikation

  • 86
  • 56
  • 52
  • 43
  • 31
  • 19
  • 17
  • 16
  • 13
  • 13
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Klon

5F7
  • Produktmerkmale

    Homo sapiens fibroblast growth factor receptor 2 (FGFR2), transcript variant 1

    Aufreinigung

    Purified from mouse ascites fluids by affinity chromatography

    Immunogen

    Full length human recombinant protein of human FGFR2 (NP_000132) produced in HEK293T cell.

    Isotyp

    IgG2a
  • Applikationshinweise

    WB 1:2000, IF 1:100, FLOW 1:100

    Kommentare

    The concentration of the product may vary between diferrent lots.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.5-1.0 mg/mL

    Buffer

    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C
  • Target

    FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

    Andere Bezeichnung

    FGFR2

    Hintergrund

    The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

    Molekulargewicht

    89.7 kDa

    Gen-ID

    2263

    NCBI Accession

    NM_000141

    HGNC

    2263

    Pathways

    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding
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