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N-Cadherin Antikörper

Name: N-Cadherin Antikörper
SKU: ABIN2716943
Price: 752.5 EUR
Availability: InStock

CDH2 Reaktivität: Human WB, IHC, FACS Wirt: Maus Monoclonal 3B10 unconjugated

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDH2 (Right lane) cDNA for 48 hrs and lysed. (N-Cadherin Antikörper)

HEK293T cells transfected with either RC207170 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-CDH2 antibody (ABIN2455182), and then analyzed by flow cytometry. (N-Cadherin Antikörper)

FACS

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-CDH2 mouse monoclonal antibody. (N-Cadherin Antikörper)

IHC

3 Abbildungen

(1 reference)

Produktnummer ABIN2716943

Datenblatt (PDF)

Target Alle N-Cadherin (CDH2) Antikörper anzeigen

N-Cadherin (CDH2) (Cadherin 2 (CDH2))
Reaktivität
158

97

69

21

18

15

8

4

3

3

3

3

2

2

2

2

2

1

1

1
Human
Wirt
99

65

4

2

2

2
Maus
Passende Sekundärantikörper
Klonalität
91

82

1
Monoklonal
Konjugat
88

15

5

5

4

4

4

4

4

4

4

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser N-Cadherin Antikörper ist unkonjugiert
Applikation
117

55

47

45

32

25

18

14

13

13

9

9

4

2

2

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktmerkmale

Homo sapiens cadherin 2, type 1, N-cadherin (neuronal) (CDH2)

Aufreinigung

Purified from mouse ascites fluids by affinity chromatography

Immunogen

Full length human recombinant protein of human CDH2(NP_001783) produced in HEK293T cell.

Klon

3B10

Isotyp

IgG2a

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anti-Cadherin 2 (CDH2) (Extracellular Domain) antibody
CDH2 Reaktivität: Human WB, IHC, IF, FACS, IHC (f) Wirt: Maus Monoclonal 8C11 unconjugated

Applikationshinweise

WB 1:2000, IHC 1:150, FLOW 1:100,

Kommentare

The concentration of the product may vary between diferrent lots.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

0.5-1.0 mg/mL

Buffer

PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C
Zhang, He, Chen, Pan, Du, Zang, Wang, Tang, Li, Lu, Yao, Jin, Ma: "Chemotherapy enhances tumor vascularization via Notch signaling-mediated formation of tumor-derived endothelium in breast cancer." in: Biochemical pharmacology, Vol. 118, pp. 18-30, (2016) (PubMed).
Target

N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Andere Bezeichnung

CDH2 (CDH2 Produkte)

Hintergrund

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.

Molekulargewicht

97.2 kDa

Gen-ID

1000

NCBI Accession

NM_001792

HGNC

1000

Pathways

Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane