ARFGAP1 Antikörper
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- Target Alle ARFGAP1 Antikörper anzeigen
- ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))
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Reaktivität
- Human, Affe
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ARFGAP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- Produktmerkmale
- Homo sapiens ADP-ribosylation factor GTPase activating protein 1 (ARFGAP1), transcript variant 2
- Aufreinigung
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of human ARFGAP1 (NP_783202) produced in HEK293T cell.
- Klon
- 2C6
- Isotyp
- IgG2b
- Top Product
- Discover our top product ARFGAP1 Primärantikörper
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- Applikationshinweise
- WB 1:500~2000, IF 1:100, FLOW 1:100
- Kommentare
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The concentration of the product may vary between diferrent lots.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))
- Andere Bezeichnung
- ARFGAP1 (ARFGAP1 Produkte)
- Hintergrund
- The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene.
- Molekulargewicht
- 45.5 kDa
- Gen-ID
- 55738
- NCBI Accession
- NM_175609
- HGNC
- 55738
- Pathways
- p53 Signalweg, ER-Nucleus Signaling, Unfolded Protein Response
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