Annexin A3 Antikörper

Produktnummer ABIN2716166

Dieser Maus Monoklonal Antikörper detektiert spezifisch Annexin A3 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human. Es wurde in 4+ Publikationen zitiert.

Kurzübersicht für Annexin A3 Antikörper (ABIN2716166)

Target: Annexin A3 (ANXA3)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Annexin A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: 1F11

Produktdetails anti-Annexin A3 Antikörper

Produktmerkmale: Homo sapiens annexin A3 (ANXA3)

Aufreinigung: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human ANXA3 (NP_005130) produced in HEK293T cell.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: WB 1:500~2000, IHC 1:150,

Kommentare:

The concentration of the product may vary between diferrent lots.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-Annexin A3 Antikörper (ABIN2716166)

Wang, Li: "Overexpression of ANXA3 is an independent prognostic indicator in gastric cancer and its depletion suppresses cell proliferation and tumor growth." in: Oncotarget, Vol. 7, Issue 52, pp. 86972-86984, (2018) (PubMed).

Pan, Pan, Weng, Zhao, Zhang, Wang, Lv, Jiang, Zheng, Xia: "Annexin A3 promotes tumorigenesis and resistance to chemotherapy in hepatocellular carcinoma." in: Molecular carcinogenesis, Vol. 54, Issue 8, pp. 598-607, (2015) (PubMed).

Pan, Pan, Wang, Weng, Zhao, Zheng, Zhang, Jiang, Lv, Tang, Li, He, Liu, Chen, Zhang, Xia: "Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells." in: Stem cells (Dayton, Ohio), Vol. 33, Issue 2, pp. 354-66, (2015) (PubMed).

Mercado, Kizawa, Ueda, Xiong, Kimura, Moses, Curtis, Ito, Barnes: "Activation of transcription factor Nrf2 signalling by the sphingosine kinase inhibitor SKI-II is mediated by the formation of Keap1 dimers." in: PLoS ONE, Vol. 9, Issue 2, pp. e88168, (2014) (PubMed).

Details zu Annexin A3

Target: Annexin A3 (ANXA3)

Andere Bezeichnung: ANXA3

Hintergrund: This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.

Molekulargewicht: 36.2 kDa

Gen-ID: 306

NCBI Accession: NM_005139

HGNC: 306