ADH1B Antikörper

Produktnummer ABIN2715877

Für dieses Produkt ist 1 Publikation verfügbar. Der Maus-Monoklonal Anti-ADH1B-Antikörper wurde für WB, IHC, IF und FACS validiert. Er ist geeignet zum Nachweis von ADH1B in Proben aus Human, Ratte und Hund. }

Kurzübersicht für ADH1B Antikörper (ABIN2715877)

Target: ADH1B (Alcohol Dehydrogenase 1B (Class I), beta Polypeptide (ADH1B))

Reaktivität: Human, Ratte, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ADH1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: 4F12

Produktdetails anti-ADH1B Antikörper

Produktmerkmale: Homo sapiens alcohol dehydrogenase 1B (class I), beta polypeptide (ADH1B)

Aufreinigung: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human ADH1B (NP_000659) produced in HEK293T cell.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: WB 1:500, IHC 1:150, IF 1:100, FLOW 1:100

Kommentare:

The concentration of the product may vary between diferrent lots.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-ADH1B Antikörper (ABIN2715877)

Samak, Gangwar, Meena, Rao, Shukla, Manda, Narayanan, Jaggar, Rao: "Calcium Channels and Oxidative Stress Mediate a Synergistic Disruption of Tight Junctions by Ethanol and Acetaldehyde in Caco-2 Cell Monolayers." in: Scientific reports, Vol. 6, pp. 38899, (2018) (PubMed).

Details zu ADH1B

Target: ADH1B (Alcohol Dehydrogenase 1B (Class I), beta Polypeptide (ADH1B))

Andere Bezeichnung: ADH1B

Hintergrund: The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster.

Molekulargewicht: 39.7 kDa

Gen-ID: 125

NCBI Accession: NM_000668

HGNC: 125