FAIM3 Antikörper (Fas Apoptotic Inhibitory Molecule 3) (AA 80-130) (Biotin)

Details for Product anti-FAIM3 Antibody No. ABIN2690130
Antigen
Epitop
AA 80-130
14
13
8
8
3
2
1
1
1
Reaktivität
Human
78
13
6
Wirt
Kaninchen
74
12
Klonalität
Polyklonal
Konjugat
Dieser FAIM3 Antikörper ist konjugiert mit Biotin
4
3
3
3
3
3
3
3
3
1
1
1
1
1
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
55
25
14
13
12
2
2
2
2
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human FAIM3
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung FAIM3 (FAIM3 Antibody Abstract)
Hintergrund

May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.

Subcellular location: Extracellular, Secreted, Cell membrane

Synonyms: TOSO, FAIM3, Fas apoptotic inhibitory molecule 3, Regulator of Fas-induced apoptosis Toso

Gen-ID 9214
UniProt O60667
Applikations-hinweise IHC-P 1:100-500
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months