FAIM3 Antikörper (AA 18-251)

Produktnummer ABIN7152579

Produktdetails anti-FAIM3 Antikörper

Target: FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))

Bindungsspezifität: AA 18-251

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAIM3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Fas apoptotic inhibitory molecule 3 protein (18-251AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FAIM3

Target: FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))

Andere Bezeichnung: FCMR (FAIM3 Produkte)

Synonyme: FAIM3 antikoerper, FCMR antikoerper, TOSO antikoerper, 1810037B05Rik antikoerper, FcmuR antikoerper, Toso antikoerper, Fc fragment of IgM receptor antikoerper, FCMR antikoerper, Fcmr antikoerper

Hintergrund:

Background: May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.

Aliases: Faim3 antibody, FAIM3_HUMAN antibody, Fas apoptotic inhibitory molecule 3 antibody, Fc fragment of IgM receptor antibody, Fc mu receptor antibody, FCMR antibody, IgM Fc receptor antibody, Immunoglobulin mu Fc receptor antibody, Regulator of Fas induced apoptosis antibody, Regulator of Fas-induced apoptosis Toso antibody, TOSO antibody

UniProt: O60667