TCR gamma/delta Antikörper

Produktnummer ABIN2689516

Zitiert in 13+ Publikationen. Der Armenischer Hamster Monoklonal anti-TCR gamma/delta Antikörper (Klon GL3) (ABIN2689516) detektiert spezifisch TCR gamma/delta in FACS, IP, IHC (fro), IF und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für TCR gamma/delta Antikörper (ABIN2689516)

Target: TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))

Reaktivität: Maus

Wirt: Armenischer Hamster

Klonalität: Monoklonal

Konjugat: Dieser TCR gamma/delta Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: GL3

Produktdetails anti-TCR gamma/delta Antikörper

Produktmerkmale: The GL3 antibody reacts with a common epitope of the δ chain of the T-cell Receptor (TCR) complex on γδ TCR-expressing T lymphocytes and NK-T cells of all mouse strains tested. It does not react with αβ TCR-bearing T cells. In the mouse, cells expressing the γδ TCR are found in the thymus, intestinal epithelium, epidermis, dermis, pulmonsry epithelium, peritoneum, liver, and peripheral lymphoid organs. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.

BD Pharmingen™ Purified Hamster Anti-Mouse γδ T-Cell Receptor - Purified - Clone GL3 - Isotype Armenian Hamster IgG2, κ - Reactivity Ms - 0.5 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: C57BL/6 Mouse Intestinal Intraepithelial Lymphocytes

Isotyp: IgG2 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C.

Referenzen für anti-TCR gamma/delta Antikörper (ABIN2689516)

King, Hyde, Jackson, Novosad, Ellis, Putney, Stovall, Van Winkle, Beaman, Ferrick: "Cutting edge: protective response to pulmonary injury requires gamma delta T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 9, pp. 5033-6, (1999) (PubMed).

Shinohara, Ikarashi, Maruoka, Miyata, Sugimura, Terada, Wakasugi: "Functional and phenotypical characteristics of hepatic NK-like T cells in NK1.1-positive and -negative mouse strains." in: European journal of immunology, Vol. 29, Issue 6, pp. 1871-8, (1999) (PubMed).

Yañez, Batchelder, van der Heyde, Manning, Weidanz: "Gamma delta T-cell function in pathogenesis of cerebral malaria in mice infected with Plasmodium berghei ANKA." in: Infection and immunity, Vol. 67, Issue 1, pp. 446-8, (1999) (PubMed).

Tamaki, Yasaka, Chang, Ohtake, Saitoh, Nakamura, Furue: "Identification and characterization of novel dermal Thy-1 antigen-bearing dendritic cells in murine skin." in: The Journal of investigative dermatology, Vol. 106, Issue 3, pp. 571-5, (1996) (PubMed).

van der Heyde, Elloso, Chang, Kaplan, Manning, Weidanz: "Gamma delta T cells function in cell-mediated immunity to acute blood-stage Plasmodium chabaudi adami malaria." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 8, pp. 3985-90, (1995) (PubMed).

Nakazawa, Brown, Maeno, Smith, Aikawa: "Malaria-induced increase of splenic gamma delta T cells in humans, monkeys, and mice." in: Experimental parasitology, Vol. 79, Issue 3, pp. 391-8, (1994) (PubMed).

Lefrançois, Barrett, Havran, Puddington: "Developmental expression of the alpha IEL beta 7 integrin on T cell receptor gamma delta and T cell receptor alpha beta T cells." in: European journal of immunology, Vol. 24, Issue 3, pp. 635-40, (1994) (PubMed).

Kaufmann, Blum, Yamamoto: "Crosstalk between alpha/beta T cells and gamma/delta T cells in vivo: activation of alpha/beta T-cell responses after gamma/delta T-cell modulation with the monoclonal antibody GL3." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 20, pp. 9620-4, (1993) (PubMed).

Skeen, Ziegler: "Induction of murine peritoneal gamma/delta T cells and their role in resistance to bacterial infection." in: The Journal of experimental medicine, Vol. 178, Issue 3, pp. 971-84, (1993) (PubMed).

Lefrancois: "Phenotypic complexity of intraepithelial lymphocytes of the small intestine." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 6, pp. 1746-51, (1991) (PubMed).

MacDonald, Schreyer, Howe, Bron: "Selective expression of CD8 alpha (Ly-2) subunit on activated thymic gamma/delta cells." in: European journal of immunology, Vol. 20, Issue 4, pp. 927-30, (1990) (PubMed).

Tigelaar, Lewis, Bergstresser: "TCR gamma/delta+ dendritic epidermal T cells as constituents of skin-associated lymphoid tissue." in: The Journal of investigative dermatology, Vol. 94, Issue 6 Suppl, pp. 58S-63S, (1990) (PubMed).

Goodman, Lefrancois: "Intraepithelial lymphocytes. Anatomical site, not T cell receptor form, dictates phenotype and function." in: The Journal of experimental medicine, Vol. 170, Issue 5, pp. 1569-81, (1989) (PubMed).

Details zu TCR gamma/delta

Target: TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))

Andere Bezeichnung: Gammadelta T-Cell Receptor