CEACAM1 Antikörper

Produktnummer ABIN2689373

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CEACAM1 in FACS. Er zeigt eine Reaktivität gegenüber Human und wurde in 4+ Publikationen erwähnt.

Kurzübersicht für CEACAM1 Antikörper (ABIN2689373)

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CEACAM1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: B1-1-CD66

Produktdetails anti-CEACAM1 Antikörper

Marke: BD Pharmingen™

Produktmerkmale: Reacts with several glycosylphosphatidylinositol-anchored glycoproteins present on granulocytes and epithelial cells. Antibody B1.1 was studied as recognizing CD66a, c, d and e in the VI Human Leukocyte Differentiation Workshop. CD66 antigens, also known as the carcinoembryonic antigen (CEA) family of molecules, are closely related to the immunoglobulin superfamily of glycoproteins. Studies on CD66 Molecules suggest a potential adhesion function in vivo. These molecules exhibit both homophilic and heterophilic ashesion. CEA family members may be involved in transmembrane signalling and activation of neutrophils. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood granulocytes analyzed by flow cytometry. Second step staining with Cat. No. 555988.

BD Pharmingen™ Purified Mouse Anti-Human CD66 - Purified - Clone B1.1/CD66 - Isotype Mouse IgG2a, κ - Reactivity Hu - 0.1 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C.

Referenzen für anti-CEACAM1 Antikörper (ABIN2689373)

Nagel, Grunert, Kuijpers, Watt, Thompson, Zimmermann: "Genomic organization, splice variants and expression of CGM1, a CD66-related member of the carcinoembryonic antigen gene family." in: European journal of biochemistry / FEBS, Vol. 214, Issue 1, pp. 27-35, (1993) (PubMed).

Kuroki, Arakawa, Matsuo, Oikawa, Misumi, Nakazato, Matsuoka: "Molecular cloning of nonspecific cross-reacting antigens in human granulocytes." in: The Journal of biological chemistry, Vol. 266, Issue 18, pp. 11810-7, (1991) (PubMed).

Thompson, Grunert, Zimmermann: "Carcinoembryonic antigen gene family: molecular biology and clinical perspectives." in: Journal of clinical laboratory analysis, Vol. 5, Issue 5, pp. 344-66, (1991) (PubMed).

Szpak, Johnston, Lottich, Kufe, Thor, Schlom: "Patterns of reactivity of four novel monoclonal antibodies (B72.3, DF3, B1.1 and B6.2) with cells in human malignant and benign effusions." in: Acta cytologica, Vol. 28, Issue 4, pp. 356-67, (1984) (PubMed).

Details zu CEACAM1

Target: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Andere Bezeichnung: CD66

Hintergrund: Synonyms: CEA, carcinoembryonic antigen