CD55 Antikörper (Biotin)

Produktnummer ABIN2689338

Der Maus Monoklonal Anti-CD55-Antikörper wurde für FACS validiert. Er ist geeignet, CD55 in Proben von Human zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für CD55 Antikörper (Biotin) (ABIN2689338)

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD55 Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS)

Klon: IA10

Produktdetails anti-CD55 Antikörper (Biotin)

Marke: BD Pharmingen™

Produktmerkmale: Reacts with CD55, decay-accelerating factor (DAF), a glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein of approximately 70 kDa, expressed on hematopoietic cells. It has been suggested that the role of DAF is to protect cells from damage by autologous complement preventing the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertases, C4b2a3b and C3bBb3b. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of K562 cells expressing glycosylphosphatidylinositol (GPI) anchored protein analyzed on a FACScan Profile of glycosylphosphatidylinositol (GPI) achor-defective mutant K562 cell line lymphocytes analyzed on a FACScan

BD Pharmingen™ Biotin Mouse Anti-Human CD55 - Biotin - Clone IA10 - Isotype Mouse IgG2a, κ - Reactivity Hu - 100 Tests

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Probenmenge: 20 μL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Referenzen für anti-CD55 Antikörper (Biotin) (ABIN2689338)

Loveland, Szokolai, Johnstone, McKenzie: "Coordinate functions of multiple complement regulating molecules, CD46, CD55, and CD59." in: Transplantation proceedings, Vol. 26, Issue 3, pp. 1070-1, (1994) (PubMed).

Kinoshita, Medof, Silber, Nussenzweig: "Distribution of decay-accelerating factor in the peripheral blood of normal individuals and patients with paroxysmal nocturnal hemoglobinuria." in: The Journal of experimental medicine, Vol. 162, Issue 1, pp. 75-92, (1985) (PubMed).

Guesdon, Ternynck, Avrameas: "The use of avidin-biotin interaction in immunoenzymatic techniques." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 27, Issue 8, pp. 1131-9, (1979) (PubMed).

Details zu CD55

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Andere Bezeichnung: CD55

Hintergrund: Synonyms: DAF

Pathways: Komplementsystem, Regulation of Leukocyte Mediated Immunity