Cadherin 5 Antikörper

Produktnummer ABIN2688979

Dieses Anti-Cadherin 5-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von Cadherin 5 in FACS, IHC (fro) und IHC (f). Geeignet für Maus. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für Cadherin 5 Antikörper (ABIN2688979)

Target: Cadherin 5 (CDH5)

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Cadherin 5 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Klon: 11D4-1

Produktdetails anti-Cadherin 5 Antikörper

Marke: BD Pharmingen™

Produktmerkmale: The 11D4.1 antibody reacts with mouse VE-cadherin, a member of the cadherin family. VE-cadherin is an endothelial cell-specific, homophilic adhesion molecule. It is concentrated at interendothelial cells contacts and is thought to be involved in the maintenance of cell layer integrity. In vitro and in vivo studies indicate that the 11D.4 mAb interferes with VE-cadherin-mediated intercellular adhesion. Immunohistochemical staining of CD144. Frozen sections of normal mouse small intestine were reacted with the anti-CD144 antibody. Cells expressing VE-Cadherin can be identified by the brown labeling of their cell membranes. Amplification 20X.

BD Pharmingen™ Purified Rat Anti-Mouse CD144 - Purified - Clone 11D4.1 - Isotype Rat IgG2a, κ - Reactivity Ms - 1 mL

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Mouse VE-Cadherin-Ig Fusion

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 125 μg/mL

Buffer: Aqueous buffered solution containing BSA, goat serum, and ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C.

Referenzen für anti-Cadherin 5 Antikörper (ABIN2688979)

Gotsch, Borges, Bosse, Böggemeyer, Simon, Mossmann, Vestweber: "VE-cadherin antibody accelerates neutrophil recruitment in vivo." in: Journal of cell science, Vol. 110 ( Pt 5), pp. 583-8, (1997) (PubMed).

Breier, Breviario, Caveda, Berthier, Schnürch, Gotsch, Vestweber, Risau, Dejana: "Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system." in: Blood, Vol. 87, Issue 2, pp. 630-41, (1996) (PubMed).

Lampugnani, Resnati, Raiteri, Pigott, Pisacane, Houen, Ruco, Dejana: "A novel endothelial-specific membrane protein is a marker of cell-cell contacts." in: The Journal of cell biology, Vol. 118, Issue 6, pp. 1511-22, (1992) (PubMed).

Details zu Cadherin 5

Target: Cadherin 5 (CDH5)

Andere Bezeichnung: CD144

Hintergrund: Synonyms: VE-Cadherin, Cadherin-5

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2