ASH2L Antikörper (N-Term)

Produktnummer ABIN2668901

Zitiert in 1 Publikation. Der Ratte Monoklonal anti-ASH2L Antikörper (Klon 4C5) (ABIN2668901) detektiert spezifisch ASH2L in WB, IHC, IF, ICC und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ASH2L Antikörper (N-Term) (ABIN2668901)

Target: ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser ASH2L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Klon: 4C5

Produktdetails anti-ASH2L Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: ASH2L antibody (mAb) (Clone 4C5)

Aufreinigung: Protein G Chromatography

Immunogen: This antibody was raised against a recombinant protein corresponding to the N-terminal region of human ASH2L.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Referenzen für anti-ASH2L Antikörper (ABIN2668901)

Lüscher-Firzlaff, Gawlista, Vervoorts, Kapelle, Braunschweig, Walsemann, Rodgarkia-Schamberger, Schuchlautz, Dreschers, Kremmer, Lilischkis, Cerni, Wellmann, Lüscher: "The human trithorax protein hASH2 functions as an oncoprotein." in: Cancer research, Vol. 68, Issue 3, pp. 749-58, (2008) (PubMed).

Details zu ASH2L

Target: ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))

Andere Bezeichnung: ASH2L

Hintergrund: ASH2L (absent, small, or homeotic)-like (Drosophila) is a component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.

Molekulargewicht: 85 kDa

Gen-ID: 9070

NCBI Accession: NP_004665