MYC-Associated Zinc Finger Protein (Purine-Binding Transcription Factor) (MAZ) Antikörper

Details zu Produkt Nr. ABIN2668733
Antigen
Reaktivität
Human
78
46
46
6
6
4
3
2
1
1
1
Wirt
Maus
62
16
Klonalität (Klon)
Monoklonal ()
Konjugat
Unkonjugiert
4
3
3
3
3
3
3
2
2
1
1
1
1
1
Applikation
Chromatin Immunoprecipitation (ChIP), Electrophoretic Mobility-Shift Assay (EMSA)
49
27
13
7
6
6
3
2
1
1
1
Optionen
Immunogen This Maz antibody was raised against recombinant human Maz protein.
Klon 133
Isotyp IgG
Reinigung Protein G Chromatography
Antigen
Andere Bezeichnung Maz (MAZ Antibody Abstract)
Hintergrund Maz (Myc-associated zinc finger protein) functions as a transcription factor roles in both transcription initiation and termination. Maz binds to two sites within the c-Myc promoter, ME1a1 and ME1a2. It also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Maz also partipates in skeletal muscle development through the activation of several skeletal muscle-specific genes. Maz has also been reported to drive tumor-specific expression of PPAR- gamma in breast cancer cells.
Molekulargewicht 55 kDa
Gen-ID 4150
Pathways Chromatin Binding
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 μg/μL
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
Lagerung -20 °C
Informationen zur Lagerung Antibodies in solution can be stored at -20 °C for 2 years.
Haltbarkeit 6 months
Produkt verwendet in: Himeda, Ranish, Hauschka: "Quantitative proteomic identification of MAZ as a transcriptional regulator of muscle-specific genes in skeletal and cardiac myocytes." in: Molecular and cellular biology, Vol. 28, Issue 20, pp. 6521-35, 2008 (PubMed).

Ashfield, Patel, Bossone, Brown, Campbell, Marcu, Proudfoot: "MAZ-dependent termination between closely spaced human complement genes." in: The EMBO journal, Vol. 13, Issue 23, pp. 5656-67, 1995 (PubMed).