MAZ Antikörper (N-Term)

Produktnummer ABIN2780422

Produktdetails anti-MAZ Antikörper

Target: MAZ (MYC-Associated Zinc Finger Protein (Purine-Binding Transcription Factor) (MAZ))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAZ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: FPVFPCTLLA PPFPVLGLDS RGVGGLMNSF PPPQGHAQNP LQVGAELQSR

Homologie: Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MAZ. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAZ

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 477 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-MAZ Antikörper (ABIN2780422)

Smits, Wurdinger, van het Hof, Drexhage, Geerts, Wesseling, Noske, Vandertop, de Vries, Reijerkerk: "Myc-associated zinc finger protein (MAZ) is regulated by miR-125b and mediates VEGF-induced angiogenesis in glioblastoma." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 26, Issue 6, pp. 2639-47, (2012) (PubMed).

Details zu MAZ

Target: MAZ (MYC-Associated Zinc Finger Protein (Purine-Binding Transcription Factor) (MAZ))

Andere Bezeichnung: MAZ (MAZ Produkte)

Synonyme: PUR1 antikoerper, Pur-1 antikoerper, SAF-1 antikoerper, SAF-2 antikoerper, SAF-3 antikoerper, ZF87 antikoerper, ZNF801 antikoerper, Zif87 antikoerper, MYC associated zinc finger protein antikoerper, MYC-associated zinc finger protein (purine-binding transcription factor) antikoerper, myc-associated zinc finger protein (purine-binding transcription factor) L homeolog antikoerper, MAZ antikoerper, Maz antikoerper, maz.L antikoerper

Hintergrund: MAZ may function as a transcription factor with dual roles in transcription initiation and termination.It binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. It also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors.
Alias Symbols: PUR1, Pur-1, SAF-1, SAF-2, ZF87, ZNF801, Zif87, SAF-3
Protein Interaction Partner: HECW2, MAPK14, BPTF, JUN, FOS, KEAP1, DCC, CSNK2A1,
Protein Size: 477

Molekulargewicht: 48 kDa

Gen-ID: 4150

NCBI Accession: NM_002383, NP_002374

UniProt: P56270

Pathways: Chromatin Binding