Aurora Kinase B Antikörper (C-Term)

Produktnummer ABIN2668672

Der Kaninchen Polyklonal anti-Aurora Kinase B Antikörper wird verwendet zum Nachweis von Aurora Kinase B in Proben von Human und Maus. Er wurde validiert für WB, IF und ICC.

Kurzübersicht für Aurora Kinase B Antikörper (C-Term) (ABIN2668672)

Target: Aurora Kinase B (AURKB)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aurora Kinase B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-Aurora Kinase B Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Aurora B antibody (pAb)

Aufreinigung: Unpurified

Immunogen: This Aurora B antibody was raised against a peptide including the C-terminus of human Aurora B.

Anwendungsinformationen

Applikationshinweise: ICC/IF: 1:200 - 1:1,000 dilution WB: 1:500 - 1:5,000 dilution

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu Aurora Kinase B

Target: Aurora Kinase B (AURKB)

Andere Bezeichnung: Aurora B

Hintergrund: Aurora B (Aurora Kinase B, AurB, ARK2) is a Ser/Thr kinase that is part of the chromosomal passenger complex that associates with chromosomes and is an important regulator of mitosis and meiosis. Aurora B becomes concentrated at the centromere during the onset of mitosis, but relocates to the spindle midzone during anaphase. Aurora B phosphorylates a number of substrates, including INCENP, CENP-A, and Histone H3. Misregulation of Aurora B activity can lead to chromosome instability and is implicated in a number of cancers.

Molekulargewicht: 49 kDa

Gen-ID: 9212

NCBI Accession: NP_004208

Pathways: T-Zell Rezeptor Signalweg, Zellzyklus, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades