PBX1 Antikörper

Produktnummer ABIN2668628

Zitiert in 2+ Publikationen. Der Maus Monoklonal anti-PBX1 Antikörper (Klon CT 41-1) (ABIN2668628) detektiert spezifisch PBX1 in WB, IHC und ChIP. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PBX1 Antikörper (ABIN2668628)

Target: PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PBX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)

Klon: CT 41-1

Produktdetails anti-PBX1 Antikörper

Verwendungszweck: PBX1b antibody (mAb) (Clone CT 41.1)

Aufreinigung: Protein G Chromatography

Immunogen: This PBX1b antibody was raised against a recombinant protein corresponding to amino acids 319 - 347 of human PBX1b.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Referenzen für anti-PBX1 Antikörper (ABIN2668628)

Park, Shih, Wang: "Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer." in: Cancer research, Vol. 68, Issue 21, pp. 8852-60, (2008) (PubMed).

Brendolan, Ferretti, Salsi, Moses, Quaggin, Blasi, Cleary, Selleri: "A Pbx1-dependent genetic and transcriptional network regulates spleen ontogeny." in: Development (Cambridge, England), Vol. 132, Issue 13, pp. 3113-26, (2005) (PubMed).

Details zu PBX1

Target: PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))

Andere Bezeichnung: PBX1b

Hintergrund: PBX proteins are a family of TALE-class transcription factors that associate with a subset of Hox proteins, enhancing their DNA binding affinities and specificities. PBX proteins also heterodimerize with the Meis/Prep subfamily of to form trimeric complexes with Hox proteins at specific DNA sites. Amino acids 348-430 are absent in isoform PBX1b.

Molekulargewicht: 40 kDa

Gen-ID: 5087

NCBI Accession: NP_001191890