PBX1 Antikörper
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- Target Alle PBX1 Antikörper anzeigen
- PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PBX1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Peptide (BP), Coating (Coat)
- Spezifität
- Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1,19)(q23,p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92 % and 94 % respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human PBX1 protein
- Isotyp
- IgG2b
- Top Product
- Discover our top product PBX1 Primärantikörper
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- Applikationshinweise
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Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa cells. Expressed in all tissues except in cells of the B and T lineage.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
- Andere Bezeichnung
- PBX1 (PBX1 Produkte)
- Synonyme
- fi29e01 antikoerper, pbx1b antikoerper, wu:fi29e01 antikoerper, zgc:55265 antikoerper, 2310056B04Rik antikoerper, AI848790 antikoerper, AU015730 antikoerper, D230003C07Rik antikoerper, Pbx-1 antikoerper, Pbx1a antikoerper, Pbx1b antikoerper, PBX1A antikoerper, Xpbx1 antikoerper, Xpbx1b antikoerper, PBX homeobox 1 antikoerper, pre-B-cell leukemia homeobox 1a antikoerper, pre B cell leukemia homeobox 1 antikoerper, pre-B-cell leukemia homeobox 1 S homeolog antikoerper, PBX1 antikoerper, pbx1a antikoerper, Pbx1 antikoerper, pbx1.S antikoerper
- Hintergrund
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DKFZp686B09108, Homeobox protein PBX 1, Homeobox protein PBX1, Homeobox protein PRL, Pbx1, Pre B cell leukemia homeobox 1, Pre B cell leukemia transcription factor 1, Pre-B-cell leukemia transcription factor 1, PRL,PBX1 / PRL (Transcription Factor)
Cellular localisation: Nucleus. - Molekulargewicht
- 86.1kDa
- Gen-ID
- 5087, 557097
- UniProt
- P40424
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