MAD2L1 Antikörper

Produktnummer ABIN2668530

Dieser Maus Monoklonal Antikörper detektiert spezifisch MAD2L1 in WB. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für MAD2L1 Antikörper (ABIN2668530)

Target: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MAD2L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 17D10

Produktdetails anti-MAD2L1 Antikörper

Verwendungszweck: MAD2L1 antibody (mAb) (Clone 17D10)

Aufreinigung: Protein G Chromatography

Immunogen: This MAD2L1 antibody was raised against full-length recombinant human MAD2L1.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 2 - 5 μg/mL dilution

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu MAD2L1

Target: MAD2L1 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1))

Andere Bezeichnung: MAD2L1

Hintergrund: MAD2L1 (aka HSMAD2, MAD2, MAD2-like 1) is the human homolog of the budding yeast MAD2, or mitotic arrest deficient 2 gene. MAD2L1 is a component of the mitotic spindle assembly checkpoint, which monitors the attachment of the mitotic spindle to the kinetochores of segregating chromosomes and delays the onset of anaphase until attachment is complete and the chromosomes are properly aligned on the metaphase plate. MAD2L1 associates only with unattached kinetochores in prometaphase, and prevents cell cycle progression by associating with the Anaphase Promoting Complex (APC), specifically restricting the activity of the CDC20 protein.

Molekulargewicht: 23 kDa

Gen-ID: 4085

NCBI Accession: NP_002349