Rpb1 CTD Antikörper (Tyr1)
Kurzübersicht für Rpb1 CTD Antikörper (Tyr1) (ABIN2668519)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- Tyr1
-
Aufreinigung
- Protein G Chromatography
-
Immunogen
- This antibody was raised against a synthetic peptide containing the RNA Pol II heptad repeat consensus sequence phosphorylated at tyrosine 1.
-
Isotyp
- IgG1
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1 μg/μL
-
Buffer
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
-
Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Antibodies in solution can be stored at -20 °C for 2 years.
-
Haltbarkeit
- 6 months
-
-
-
: "Comprehensive RNA Polymerase II Interactomes Reveal Distinct and Varied Roles for Each Phospho-CTD Residue." in: Cell reports, Vol. 15, Issue 10, pp. 2147-2158, (2016) (PubMed).
: "CDK9 inhibitors define elongation checkpoints at both ends of RNA polymerase II-transcribed genes." in: Nature structural & molecular biology, Vol. 22, Issue 5, pp. 396-403, (2015) (PubMed).
: "Herpes Simplex Virus 1 (HSV-1) ICP22 protein directly interacts with cyclin-dependent kinase (CDK)9 to inhibit RNA polymerase II transcription elongation." in: PLoS ONE, Vol. 9, Issue 9, pp. e107654, (2014) (PubMed).
: "CTD tyrosine phosphorylation impairs termination factor recruitment to RNA polymerase II." in: Science (New York, N.Y.), Vol. 336, Issue 6089, pp. 1723-5, (2012) (PubMed).
-
-
- Rpb1 CTD (RNA Polymerase II CTD)
-
Andere Bezeichnung
- RNA Pol II CTD
-
Molekulargewicht
- 210 kDa
-
Gen-ID
- 5430
Target
-