HIPK2 Antikörper (AA 898-1051)

Produktnummer ABIN2668288

Es gibt 1 Publikation für dieses Produkt. Der Maus Monoklonal anti-HIPK2 Antikörper wird verwendet zum Nachweis von HIPK2 in Proben von Human. Er wurde validiert für WB, IHC, IP, ICC und IF.

Kurzübersicht für HIPK2 Antikörper (AA 898-1051) (ABIN2668288)

Target: HIPK2 (Homeodomain Interacting Protein Kinase 2 (HIPK2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HIPK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)

Klon: 3E9

Produktdetails anti-HIPK2 Antikörper

Bindungsspezifität: AA 898-1051

Verwendungszweck: HIPK2 antibody (mAb) (Clone 3E9)

Aufreinigung: Protein G Chromatography

Immunogen: This HIPK2 antibody was raised against a recombinant protein including amino acids 898-1051 of mouse HIPK2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Referenzen für anti-HIPK2 Antikörper (ABIN2668288)

Isono, Nemoto, Li, Takada, Suzuki, Katsuki, Nakagawara, Koseki: "Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals." in: Molecular and cellular biology, Vol. 26, Issue 7, pp. 2758-71, (2006) (PubMed).

Details zu HIPK2

Target: HIPK2 (Homeodomain Interacting Protein Kinase 2 (HIPK2))

Andere Bezeichnung: HIPK2

Hintergrund: HIPK2 (Homeodomain Interacting Protein Kinase 2) is a serine/threonine kinase present in the nucleus that interacts with homeodomain transcription factors and acts as a co-repressor of transcription. It inhibits cell growth, as well as promotes apoptosis through the phosphorylation and subsequent degradation of the anti-apoptotic factor CTBP1. HIPK2 also phosphorylates CBX4 upon DNA damage and promotes its E3 SUMO-protein ligase activity.

Molekulargewicht: 130 kDa

Gen-ID: 28996

NCBI Accession: NP_034563

Pathways: Zellzyklus