GPR177/WLS Antikörper

Produktnummer ABIN2666414

Produktdetails anti-GPR177/WLS Antikörper

Target: GPR177/WLS (WLS) (Wntless Homolog (WLS))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GPR177/WLS Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: YJ5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Upon receipt, store undiluted between 2°C and 8°C.

Details zu GPR177/WLS

Target: GPR177/WLS (WLS) (Wntless Homolog (WLS))

Andere Bezeichnung: Wntless (WLS Produkte)

Synonyme: C1orf139 antikoerper, EVI antikoerper, GPR177 antikoerper, MRP antikoerper, mig-14 antikoerper, 5031439A09Rik antikoerper, AI173978 antikoerper, AI987742 antikoerper, Gpr177 antikoerper, gpr117 antikoerper, gpr177 antikoerper, sb:cb610 antikoerper, wu:fb36d04 antikoerper, wu:fb44d10 antikoerper, wu:fb50c06 antikoerper, zgc:64091 antikoerper, CG6210 antikoerper, Dmel\\CG6210 antikoerper, Evi antikoerper, Evi/Wls antikoerper, Srt antikoerper, Wls antikoerper, Wls/Evi antikoerper, evi antikoerper, srt antikoerper, wls/evi antikoerper, wntless Wnt ligand secretion mediator antikoerper, wntless homolog (Drosophila) antikoerper, wntless antikoerper, WLS antikoerper, Wls antikoerper, wls antikoerper

Hintergrund: Wnt signaling plays important roles in embryonic development and cancer formation. Wntless (GPR177) is a putative G-protein coupled receptor that regulates Wnt's trafficking and secretion. It can regulate the expression, subcellular location, binding, and organelle-specific association of Wnt proteins. In mammals, Wntless is mainly expressed in submucosa, muscle, ganglia, and nerve cells of the large intestines. Overexpression of Wntless may activate the NF-κB signaling pathway in cancer cells.

Pathways: WNT Signalweg